Vitamin B12
starting at $99/mo
FSA/HSA eligible
Free shipping
Nasal Spray: daily, fast-acting
Injection: Fast-acting
Nasal Spray: contains B12 (methylcobalamin) and Synapsin
Injection: contains B12 (methylcobalamin)
When you’re deficient in B12, supplementing may help improve energy levels and support cognitive and nervous system function, DNA repair, red blood cell production, and immune system health.
Potential Benefits
Cognitive function and mental clarity
Mood stabilization and mental well-being
Energy support
Immune system support
Neurological health and brain support
Neuroprotective effects
Healthy aging and neuroplasticity support
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Nasal Spray: Methylcobalamin w/ Synapsin 2000mcg/mL
Injection: Methylcobalamin 5000mcg/mL
Injection version includes subcutaneous injection needles.
If approved, appropriate dose will be determined by a licensed healthcare provider during your complimentary online exam.
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Medication is designed for absorption into the bloodstream via intranasal or injectable routes, which may allow systemic delivery without passing through the GI tract. Individual absorption may vary.
Nasal Spray: Sprayed into nostrils
Injection: Subcutaneous injection into the fat with a small needle. Includes subcutaneous needles.
Vitamin B12 is essential for nerve health, brain function, and energy production. It acts as a co-factor in several critical processes that keep your nervous system and cells working properly.
• Enhanced cognitive function & mental clarity
B12 is required to make and maintain myelin, the protective coating around nerves. Healthy myelin helps nerve signals travel faster and more accurately, supporting focus, memory, and clear thinking.• Mood stabilization & mental well-being
B12 plays a role in producing neurotransmitters like serotonin and dopamine. These brain chemicals help regulate mood and emotional balance.• Increased energy
B12 helps convert the food you eat into usable cellular energy (ATP). Without enough B12, cells can’t efficiently make energy, which can lead to fatigue.• Immune system support
B12 supports DNA synthesis and healthy cell division, which is essential for producing immune cells that protect the body.• Neurological health & brain support
B12 maintains nerve integrity and supports communication between brain cells, helping preserve overall brain function.• Neuroprotective effects
By reducing homocysteine levels (a compound linked to nerve and vascular damage), B12 helps protect brain and nerve tissue over time.• Healthy aging & neuroplasticity support
B12 supports ongoing brain cell repair and adaptation, helping the brain maintain flexibility (neuroplasticity) as we age.Synapsin (Nasal Spray version only) is a blend of two key ingredients: ginsenoside Rg3 (from ginseng) and nicotinamide riboside (NR). It’s commonly used in non-sterile products to support brain cell health and cognitive function. Rg3 helps protect nerve cells by supporting healthy brain immune activity and overall neuron function. Nicotinamide riboside (NR) helps your cells maintain healthy levels of NAD+, a molecule that’s essential for energy production and cellular repair—especially important in brain cells.
Synapsin combined with methylcobalamin may help support brain function, mental clarity, and overall neurological health.
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What is methylcobalamin (vitamin B12)?
Methylcobalamin is the biologically active form of vitamin B12, a water-soluble vitamin that plays an essential role in DNA synthesis, red blood cell formation, and normal neurological function.What is Synapsin in the nasal spray?
Synapsin includes ginsenoside Rg3 (derived from ginseng) and nicotinamide riboside (a precursor to NAD+). Ginsenoside Rg3 has been studied for potential neuroprotective and antioxidant properties. Nicotinamide riboside serves as a precursor to NAD+, a coenzyme involved in cellular energy production and mitochondrial function. Together, these components are intended to support neuronal health and cellular metabolism.What’s the difference between methylcobalamin and cyanocobalamin?
Both methylcobalamin and cyanocobalamin are forms of vitamin B12, but they differ in how the body processes them. Methylcobalamin is the naturally occurring bioactive form of B12, meaning it’s already in a form your body can use directly. Cyanocobalamin is a synthetic form of B12 that must be converted by the body into active forms (including methylcobalamin) before it can be used. Both forms can raise B12 levels in the body.What are the potential benefits?
It may support mental clarity, focus, mood balance, energy levels, neurological health, and healthy aging. Many people use it as part of a wellness plan to support cognitive performance and reduce fatigue.How does the nasal spray work?
The nasal route allows the ingredients to absorb through the nasal lining, which can offer quicker delivery compared to oral supplements. This method is often used when better absorption is desired.Is this better than taking oral B12?
Using the nasal spray or injection can be a good option for those who have trouble absorbing vitamins through the gut.How do I use the Nasal Spray?
Use the spray exactly as prescribed by your healthcare provider. Do not use more often than directed. Try to avoid using it when your nose is very congested for best absorption.Is this a prescription product?
Yes. This is a compounded prescription medication that requires evaluation and approval by a licensed healthcare provider.Are there any side effects?
Please refer to the medication information linked on this page.Who should NOT use this medication?
Please refer to the medication information linked on this page. Make sure to discuss your current medications and health history with your provider to see if this medication is appropriate for you.Can it interact with other medications or supplements?
It may. Always share a full list of your medications and supplements with your provider so they can check for possible interactions.What should I do if I miss a dose?
If you miss a dose, take it when you remember unless it’s close to your next scheduled dose. Do not double up doses.
Disclaimer: Products are only available if prescribed after an online consultation with a licensed healthcare provider. Compounded medications are dispensed by third-party USA licensed pharmacies. The Food and Drug Administration does not review compounded medications for safety or effectiveness and the statements on this page have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent diseases. Results may vary. Discontinue use and seek care if you if you experience any adverse reaction to this product. Product is offered by subscription which you can cancel anytime. Photo is for illustration purposes; actual packaging may differ.
Related Products:
NAD+
MIC+B12
Glutathione
B12 Benefits
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Cognitive Clarity
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Energy
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Mental Wellbeing
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Immune System Support
Do nasal sprays really work?
This delivery method is well known in medicine.
Nasal sprays are absorbed through the nasal mucosa. This area has rich blood vessel networks, which may allow medication to enter systemic circulation and bypass the gut.
This route is widely used in healthcare. For example, medications such as intranasal naloxone use this pathway for rapid delivery.
While injectable medications often provide high bioavailability, nasal sprays offer a needle-free alternative.
Rely on Birdie for elevated needle-free options. No needles. Just progress.
Disclaimer: The effectiveness of any medication depends on the specific drug, formulation, and individual patient factors. Results may vary and are not guaranteed.
More lift. Less drag.
Vitamin B12
Rise into steady, lasting energy.
B12 supports red blood cell production, nerve health, the immune system, and cellular metabolism — helping convert the food you eat into usable energy so you can feel clear, capable, and ready to take flight.
Formats to fit your lifestyle:
Nasal Spray: daily, easy
Injection: Fast-acting
High-level care, wherever you are.
24/7 Online provider support
Manage treatments online
Free delivery to your door
You may also be interested in
MIC+B12
How Birdie Online Works
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Step 1
HEALTH QUESTIONNAIRE
Complete a no-obligation form online about your health history and goals for treatment.
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Step 2
COMPLIMENTARY EVALUALTION
Meet with a licensed healthcare provider 100% online to see if you qualify for a treatment plan.
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Step 3
FAST & FREE SHIPPING
If approved, your prescription will ship directly to you. Get regular online check-ins and support.
High Standards. High Quality.
Birdie partners with licensed pharmacies to provide lab-tested, quality medications.
Compounded in the U.S.A.
Third-party tested for quality control
Popular Products
Designed to elevate.
Grounded in research.
Research is our passion- check out some B12 articles:
Ali, A. A. H. A., Mohamed, F. H. A., Hago, S., Elsadig Elgali, I. F., Mohammed, H. E. S., & Mirghani, R. G. (2025). The neurological sequelae of vitamin B12 deficiency: A systematic review and randomized controlled trial. Cureus, 17(5), e83668. https://doi.org/10.7759/cureus.83668
Ji, Y., Tan, S., Xu, Y., Chandra, A., Shi, C., Song, B., Qin, J., & Gao, Y. (2013). Vitamin B supplementation, homocysteine levels, and the risk of cerebrovascular disease: A meta-analysis. Neurology, 81(15), 1298–1307. https://doi.org/10.1212/WNL.0b013e3182a823cc
Ueno, A., Tanaka, K., Shibata, M., et al. (2022). Influences of vitamin B12 supplementation on cognition and homocysteine in patients with vitamin B12 deficiency and cognitive impairment. Nutrients, 14(7), 1494. https://doi.org/10.3390/nu14071494